The Senior Director, Toxicology is a key member of preclinical development teams and be responsible for the strategic planning and execution of nonclinical safety plans of Dyne’s portfolio programs supporting late discovery through first-in-human and proof-of-concept clinical studies of investigational therapeutics consisting of targeting antibodies s conjugated with a variety of oligonucleotide and protein payloads to treat serious neuromuscular diseases. The person in this role must possess an in-depth understanding of regulatory guidance as they pertain to the nonclinical development of novel therapeutics along with documented experience designing and critically evaluating results of exploratory and GLP-compliant toxicology studies. Previous experience in authoring and reviewing nonclinical regulatory documents as well as interactions with regulatory authorities is required. This individual should have experience in the nonclinical safety assessment of therapeutic antibodies and/or oligonucleotides. The ability to work collaboratively with cross-functional teams is critical for this position.

This role is based in Waltham, MA without the possibility of being a remote role.